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Retrospective Study of Bone Mineral Density through Phantom-Less Quantitative CT
1. Introduction Osteoporosis is a bone disease characterized by low bone mineral density (BMD) and micro-architectural deterioration of bone tissue [1]. BMD measurement by using dual-energy X-ray absorptiometry (DXA) is defined by the World Health Organization (WHO) Working Group as the gold standard and is clinically used to diagnose osteoporosis [2]. BMD is clearly one of the major determinants of bone strength and fracture risk [3]-[5].
Klotho regulates the myogenic response of muscle to mechanical loading and exercise
1 INTRODUCTION Changes in the mechanical environment of muscle cells can modify the expression of genes that regulate the course of myogenesis. Genes encoding the myogenic regulatory factors myoblast differentiation 1 (MyoD) and myogenin are among the transcripts expressed by developing muscle cells that are sensitive to changes in the mechanical environment.
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