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Alice Fabarius on Muck Rack

Alice Fabarius

As seen in: Nature, JoVE- Journal of Visualized Experiments
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Articles

Defining therapy goals for major molecular remission in chronic myeloid leukemia: results of the randomized CML Study IV

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By Alice Fabarius, Susanne Saussele, Rüdiger Hehlmann, Sabine Jeromin
| Nature Verified
The aim of this analysis was to define treatment failure with respect to MMR. We sought to find the landmark showing the largest difference between patients in MMR and those without any remission with regard to PFS. This landmark was found at 2.5 years and was successfully validated in an independent patient sample.
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Immunofluorescence Microscopy of γH2AX and 53BP1 for Analyzing the Formation and Repair of DNA Double-strand Breaks

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By Wolf-Karsten Hofmann, Susanne Brendel, Alice Fabarius
| JoVE- Journal of Visualized Experiments
Immunofluorescence microscopy of ?H2AX and 53BP1 is a useful method for analyzing formation and repair of DSB in a broad spectrum of research areas. Critical parameters that influence the outcome of the experiments are the phase of the cell cycle, the agents used for the fixation and permeabilization of the cells, the choice of the antibodies, and the hardware and software of the fluorescence microscope.
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