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Alissa L Parmenter on Muck Rack

Alissa L Parmenter

As seen in: Nature, BioRxiv
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Articles

The embryonic origins of site-specific arthritis

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By Sarah Davidson, Davide L. Simone, Kathrin U Jansen, Max Cowan, Caio Machado, Ian Reekie, Ananya Bhalla, Rowie Borst, Cesar Medina Verified, Joshua A. Bull, Zhi Yi Wong, Sarah Hill, Micon Garvilles, Sam Pledger, Patricia Reis Nisa, Dylan Windell, Moustafa Attar, Andrew J. Bodey, Alissa L Parmenter, Helen Byrne, Sharif U. Ahmed, Shashidhara Marathe, Peter Lee, Chris Mahony, Adam P Croft, Stephen N. Sansom, Mark Coles, Christopher Buckley, Nora Rebecca Schwingen
| Nature Verified
Abstract The cellular basis for site-specific inflammation remains unclear. In human fingers, proximal interphalangeal (PIP) joints are preferentially affected by inflammatory arthritis, whereas distal interphalangeal joints are spared, providing a model to investigate the predilection of inflammation to distinct sites.
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Synchrotron Tomography-Based Finite Element Analysis of Vertebral Endplate Loading Reveals Functional Roles for Architectural Features

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By Jishizhan Chen, Aikta Sharma, Elis Newham, Alissa L Parmenter
| BioRxiv
Abstract Lower back pain is linked to vertebral biomechanics, with vertebral endplates (VEPs) playing a key role in vertebral load transfer and distribution. Synchrotron computed tomography (sCT) allows for detailed visualisation of the microstructure of intact VEPs under near-physiological loads and, when coupled with digital volume correlation (DVC), can be used to quantify three-dimensional (3D) strain fields with nanoscale resolution.
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