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Allie Barrett on Muck Rack

Allie Barrett

As seen in: Nature, Wiley Online Library
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Articles

Engineering pyroptotic vesicles as personalized cancer vaccines - Nature Nanotechnology

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By Zhaoting Li, Yixin Wang, Fanyi Mo, Tyler Wolter, Rachel Hong, Allie Barrett, Fengyuan Liu, Yu Chen, Xicheng Yang, Lauren Dempsey
| Nature Verified
Abstract Tumour vaccines are designed to stimulate the host’s immune system against existing tumours or tumour recurrence. However, individual differences, tumour heterogeneity and side effects hinder the applications of current tumour vaccines and require the development of personalized cancer vaccines. To overcome these challenges, we engineered pyroptotic vesicles—extracellular vesicles formed during tumour cell pyroptosis—as a tumour vaccine platform.
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Nanotechnology‐Assisted CAR‐T‐Cell Therapy for Tumor Treatment

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By Yixin Wang, Quanyin Hu, Allie Barrett
| Wiley Online Library Verified
Conflicts of Interest The authors declare no conflicts of interest. References , , , et al. 2023. “Spleen SORT LNP Generated In Situ CAR T Cells Extend Survival in a Mouse Model of Lymphoreplete B Cell Lymphoma.” Angewandte Chemie (International Ed. in English) 62, no. 44: e202310395. https://doi.org/10.1002/anie.202310395. , , , , and . 2022. “The Clinical Progress of mRNA Vaccines and Immunotherapies.” Nature Biotechnology 40, no. 6: 840–854. https://doi.org/10.1038/s41587-022-01294-2. , and . 2019.
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