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Alon Goren

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Articles

Improved spike-in normalization clarifies the relationship between active histone modifications and transcription

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By Lauren Patel, Yuwei Cao, Lingzhi Zhang, Eric M. Mendenhall, Sven Heinz, Itamar Simon, Christopher K. Benner, Alon Goren, Tianyao Xu, Eduardo Modolo, Tamar Dishon
| Nature Verified
Abstract Spike-in normalization enables quantitative analysis of chromatin immunoprecipitation sequencing (ChIP-seq) signal. Here we introduce a robust dual spike-in normalization approach for ChIP-seq (ChIP-wrangler), optimize parameters and verify its accuracy in quantifying changes in ChIP-seq signal and detecting technical artifacts. We use ChIP-wrangler to revisit recent claims that active histone marks depend on transcription.
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Why RAG Alone Isn't Enough To Achieve Real ROI In The Agentic AI Era

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By Alon Goren
| Flipboard
RFK Jr.’s cancellation of mRNA vaccine research is even worse than it first seemed On first glance, the data that Health and Human Services Secretary Robert F. Kennedy Jr. cited to justify canceling some $500 million in federal grants for mRNA vaccine research looked impressive. The data, according to the agency, were embodied in some 400 research papers listed in a compilation …
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Why RAG Alone Isn't Enough To Achieve Real ROI In The Agentic AI Era

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By Alon Goren
| Forbes Verified
Alon Goren, CEO and Cofounder of AnswerRocket, transforming your analytics with AI. getty If you looked under the hood of generative AI (GenAI) technologies over the last year or so, you probably came across the concept of retrieval augmented generation (RAG). RAG has gained a lot of buzz, celebrated as a helpful innovation that enables AI to deliver more accurate, powerful insights from data. But there’s a problem: RAG isn’t the AI panacea that many organizations have envisioned.
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