Altuna Akalin on Muck Rack

Altuna Akalin

Berlin, Germany
As seen in: Nature, Genome Biology, Routledge, Towards Data Science, medRxiv
Head of bioinformatics @MDC_berlin/@BIMSB_MDC 🛠 loves genomics, R, data science, machine learning, visualization & 🎣. also @arcas_ai
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Articles

Stability and Individuality of ECG Foundation Model Embeddings in a Longitudinal Case Study

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By Altuna Akalin, Anna Domanska-Akalin
| preprints.org
Submitted: 26 January 2026 You are already at the latest version Portable ECG devices enable frequent, real-world cardiac monitoring, yet the longitudinal behavior of modern ECG foundation model representations derived from such data remains poorly characterized. In this work, we present a 20-day longitudinal case study examining the temporal stability and individual specificity of ECG representations obtained from a pretrained foundation model applied to consumer-grade six-lead ECG recordings.
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Herpesviruses mimic zygotic genome activation to promote viral replication - Nature Communications

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By Eva Neugebauer, Jiang Shan Tan, Vedran Franke, Michiel van Gent, Savas Tay, Altuna Akalin, Markus Landthaler, Armin Ensser, Emanuel Wyler, Isabelle Welker
| Nature
Abstract Zygotic genome activation (ZGA) is crucial for maternal to zygotic transition at the 2-8-cell stage in order to overcome silencing of genes and enable transcription from the zygotic genome. In humans, ZGA is induced by DUX4, a pioneer factor that drives expression of downstream germline-specific genes and retroelements.
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Evaluating large language model workflows in clinical decision support: referral, triage, and diagnosis

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By Maqsood Shaik, Vedran Franke, Altuna Akalin, Farieda Gaber
| medRxiv
The authors have declared no competing interest. AA and MS were supported by Helmholtz KA-TVP-60 grant. I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.
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