Skip To Main Content
Alyssa E. Barry on Muck Rack

Alyssa E. Barry

As seen in: Nature, GlobeNewswire, The Lancet, Cell Press
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with Alyssa E.

Contact Alyssa E., search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

Author Correction: Aryl amino acetamides prevent Plasmodium falciparum ring development via targeting the lipid-transfer protein PfSTART1 - Nature Communications

|
By Coralie Boulet, Cindy Evelyn, Niall Geoghegan, Michael J. Mlodzianoski, Dawson B Ling, Thorey K. Jonsdottir, Mojca Kristan, Colin J Sutherland, Michael J. Delves, Alyssa E. Barry, Kelly L. Rogers, Alan F. Cowman, Wai-Hong Tham, Brad E. Sleebs
| Nature Verified
Correction to: Nature Communications https://doi.org/10.1038/s41467-024-49491-8, published online 18 June 2024 The original version of the Supplementary Information associated with this Article contained an error in Supplementary Fig. 7c and d, in which the concentrations of W-991 were provided on the x-axes in the wrong order. The HTML has been updated to include a corrected version of the Supplementary Information.
Open in Who Shared View Duplicates (5) Issue with article?

Aryl amino acetamides prevent Plasmodium falciparum ring development via targeting the lipid-transfer protein PfSTART1 - Nature Communications

|
By Coralie Boulet, Cindy Evelyn, Niall Geoghegan, Michael J. Mlodzianoski, Dawson B Ling, Thorey K. Jonsdottir, Mojca Kristan, Colin J Sutherland, Michael J. Delves, Alyssa E. Barry, Kelly L. Rogers, Alan F. Cowman, Wai-Hong Tham, Brad E. Sleebs
| Nature Verified
Abstract With resistance to most antimalarials increasing, it is imperative that new drugs are developed. We previously identified an aryl acetamide compound, MMV006833 (M-833), that inhibited the ring-stage development of newly invaded merozoites. Here, we select parasites resistant to M-833 and identify mutations in the START lipid transfer protein (PF3D7_0104200, PfSTART1). Introducing PfSTART1 mutations into wildtype parasites reproduces resistance to M-833 as well as to more potent analogues.
Open in Who Shared Issue with article?

Malaria outbreak in Laos caused by formerly rare artemisinin resistant strains of Plasmodium falciparum

|
By Alyssa E. Barry
| The Lancet Verified
These results strongly suggest that the outbreak was driven by a selective sweep, possibly associated with multidrug-resistant phenotypes of the outbreak strains. Established resistant populations can circulate at low frequencies for years before suddenly overwhelming dominant strains when the conditions for selection become favourable—eg, when front-line therapies change.
Open in Who Shared Issue with article?
See all 7 articles