Amandla Mabona on Muck Rack

Amandla Mabona

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Articles

InstaNovo enables diffusion-powered de novo peptide sequencing in large-scale proteomics experiments - Nature Machine Intelligence

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By Kevin Eloff, Konstantinos Kalogeropoulos, Amandla Mabona, Oliver Morell, Marcin J. Skwark, Andreas Hougaard Laustsen, Anne Ljungars, Erwin M. Schoof, Rachel Catzel, Jeroen Van Goey
| Nature Verified
Abstract Mass spectrometry-based proteomics focuses on identifying the peptide that generates a tandem mass spectrum. Traditional methods rely on protein databases but are often limited or inapplicable in certain contexts. De novo peptide sequencing, which assigns peptide sequences to spectra without prior information, is valuable for diverse biological applications; however, owing to a lack of accuracy, it remains challenging to apply.
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De novo peptide sequencing with InstaNovo: Accurate, database-free peptide identification for large scale proteomics experiments

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By Kevin Eloff, Konstantinos Kalogeropoulos, Oliver Morell, Amandla Mabona
| biorxiv.org
Abstract Bottom-up mass spectrometry-based proteomics is challenged by the task of identifying the peptide that generates a tandem mass spectrum. Traditional methods that rely on known peptide sequence databases are limited and may not be applicable in certain contexts.
Open in Who Shared Issue with article?

De novo peptide sequencing with InstaNovo: Accurate, database-free peptide identification for large scale proteomics experiments

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By Kevin Eloff, Konstantinos Kalogeropoulos, Oliver Morell, Amandla Mabona
| biorxiv.org
Abstract Bottom-up mass spectrometry-based proteomics is challenged by the task of identifying the peptide that generates a tandem mass spectrum. Traditional methods that rely on known peptide sequence databases are limited and may not be applicable in certain contexts.
Open in Who Shared Issue with article?
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