Annekatrine Kirketerp-Møller on Muck Rack

Annekatrine Kirketerp-Møller

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InstaNovo-P: a de novo peptide sequencing model for phosphoproteomics

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By Jesper Lauridsen, Vahap Canbay, Rachel Catzel, Pathmanaban Ramasamy, Amandla Mabona, Kevin Eloff, Paul Fullwood, Jennifer Ferguson, Tine Claeys, Sam van Puyenbroeck, Nicolas Lopez Carranza, Erwin M. Schoof, Lennart Martens, Jeroen Van Goey, Chiara Francavilla, Timothy Jenkins, Konstantinos Kalogeropoulos, Annekatrine Kirketerp-Møller, Ida Sofie Goldschmidt
| Nature Verified
Abstract Phosphorylation, a crucial post-translational modification (PTM), plays a central role in cellular signaling and disease mechanisms. Mass spectrometry-based phosphoproteomics is widely used for system-wide characterization of phosphorylation events. However, traditional methods struggle with accurate phosphorylated site localization, complex search spaces, and detecting sequences outside the reference database.
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