Amik Munankarmy on Muck Rack

Amik Munankarmy

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Articles

MacroH2A histone variants modulate enhancer activity to repress oncogenic programs and cellular reprogramming - Communications Biology

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By Wazim Mohammed Ismail, Amelia Mazzone, Stephanie L. Safgren, Neda Dadgar, Jian Zhong, Jeong-Heon Lee, Tamas Ordog, Amik Munankarmy, Monique S. Bagwell, Kelsey A. Leach
| Nature Verified
Abstract Considerable efforts have been made to characterize active enhancer elements, which can be annotated by accessible chromatin and H3 lysine 27 acetylation (H3K27ac). However, apart from poised enhancers that are observed in early stages of development and putative silencers, the functional significance of cis-regulatory elements lacking H3K27ac is poorly understood.
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