Amittha Wickrema on Muck Rack

Amittha Wickrema

United States
As seen in: Nature, MedicalLab
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Articles

Chromatin rewiring of β-globin and MYC enhancers by TGF-β1 drives defective erythropoiesis

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By Srinivas Aluri, Kimo Bachiashvili, Jong Jin Jeong, Shanisha Gordon-Mitchell, Samarpana Chakraborty, Jung-In Yang, Srabani Sahu, Sanjay Pandey , Mahinder Paul, Wenjun Deng, Rahul Sanawar, Leah Kravets, Sarah Aminov, Ritesh Aggarwal, Beamon Agarwal, Divij Verma, Gaurav Choudhary, Tushar D. Bhagat, Milagros Carbajal, Rongbao Zhao, Kith Pradhan, Shahina Maqbool, Seong-Jin Kim, Ulrich Steidl, Aditi Shastri, Marc H.G.P. Raaijmakers, Andrea Pellagatti, Jacqueline Boultwood, Amittha Wickrema, Anjali Budhathoki, Micheal Sandhu, Plabani Sahu
| Nature
Abstract Erythropoiesis is a tightly regulated process involving rapid cell proliferation with orderly differentiation to ensure production of millions of RBCs. TGF-β1 is a key regulator of erythropoiesis, however, the mechanisms via which it regulates erythropoiesis are not well elucidated. Using myelodysplastic syndromes patient samples, we show that elevated TGF-β1 and SMAD2 signaling correlates with the degree of anemia.
Open in Who Shared Issue with article?

MedicalLab Management Magazine

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By Amittha Wickrema
| MedicalLab
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Open in Who Shared View Duplicates (5) Issue with article?

June 2025 - MedicalLab Management Magazine

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By David McCormick , David Mccormick, Wilson Vientos, Tyler Radke, Amittha Wickrema
| MedicalLab
Liquid Handling Platform Veya from Tecan is a liquid handling platform designed to bring efficiency, precision, and compliance to laboratories of all sizes. The system was created... Read more Laboratory Equipment Expansion NuAire has joined the Kewaunee Scientific Corporation family of companies. Together, Kewaunee and NuAire now offer a complete portfolio of furniture, fume...
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