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Abstract Convergence and extension (C&E) cell movements that elongate the primary embryonic axis are precisely timed during vertebrate gastrulation, but mechanisms controlling their onset remain unknown. Using zebrafish embryonic explants that recapitulate C&E and its timing, we identified sulfatase modifying factor 2 (sumf2) as a candidate trigger gene for C&E onset.
Introduction Click to copy section linkSection link copied! Glycosaminoglycans (GAGs) are essential polysaccharides found abundantly in the extracellular matrix (ECM) and on the cell surface of all animal cells, and they play pivotal roles in various physiological processes such as cell signaling, adhesion, and tissue development.
Introduction Click to copy section linkSection link copied! Glycosaminoglycans (GAGs) are essential polysaccharides found abundantly in the extracellular matrix (ECM) and on the cell surface of all animal cells, and they play pivotal roles in various physiological processes such as cell signaling, adhesion, and tissue development.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.