Amritha Harikumar

Abstract Schizophrenia involves well-documented disruptions of large-scale brain coordination, but how strongly networks engage one another, and how that engagement recovers when disrupted, remains poorly understood. We identify amplitude proportionality, the maintenance and recovery of matched engagement strength between networks, as a core dimension of coordination, largely obscured by intrinsic timescale differences.

Introduction Functional magnetic resonance imaging (fMRI) has shed light on the functional activity of the human brain. “Functional connectivity” (FC) is defined as correlations of spontaneous functional activity between different brain regions. These functionally correlated or connected regions collectively form functional networks (van den Heuvel et al., 2010; see review by Lee et al. 2013).

Primary and secondary structural data from the internal transcribed spacer two (ITS2) have been used extensively for diversity studies of many different eukaryotic organisms, including the green algae. Ease of amplification is due, at least in part, to the fact that ITS2 is part of the tandemly-repeated rRNA array. The potential confounding influence of intragenomic variability has yet to be addressed except in a few organisms.