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Endothelial cell‐specific progerin expression does not cause cardiovascular alterations and premature death
ECs endothelial cells HGPS Hutchinson-Gilford progeria syndrome VSMCs vascular smooth muscle cells 1 INTRODUCTION Hutchinson-Gilford progeria syndrome (HGPS) is an ultrarare genetic disease affecting 1 in 19 million people that induces accelerated aging and premature death at an average age of 14.5 years (Gordon et al., 1993).
Endothelial YAP/TAZ activation promotes atherosclerosis in a mouse model of Hutchinson-Gilford progeria syndrome
ResearchAgingVascular biology Open Access | 10.1172/JCI173448 J Clin Invest. https://doi.org/10.1172/JCI173448. Copyright © 2024, Barettino et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
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