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Analisa Thompson Gray

As seen in: ACS Publications, The Journal of Clinical Investigation
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Articles

Highly Potent and Subtype-Selective Sperm-Specific Potassium Channel 3 Inhibitors Display High Tissue Exposure in the Murine Female Reproductive Tract

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By Ping Li, Analisa Thompson Gray, Kayla J. Temple, Hallie G. McKinnie
| ACS Publications
In the United States, roughly 45% (40% worldwide) of pregnancies are unintended. (1) This high rate has been attributed to inadequate access to or incorrect use of available contraceptives. While the typical female birth control pill is 93–99% effective at preventing pregnancy, this only holds true when used perfectly.
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Gβγ-SNAP25 exocytotic brake removal enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity

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By Ryan P. Ceddia, Zack Zurawski, Analisa Thompson Gray, Feyisayo Adegboye
| The Journal of Clinical Investigation
Abstract Negative regulation of exocytosis from secretory cells is accomplished through inhibitory signals from Gi/o GPCRs by Gβγ subunit inhibition of 2 mechanisms: decreased calcium entry and direct interaction of Gβγ with soluble N-ethylmaleimide–sensitive factor attachment protein (SNAP) receptor (SNARE) plasma membrane fusion machinery.
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