Anderson S. Peck on Muck Rack

Anderson S. Peck

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Phosphorylation of TXNIP by AKT Mediates Acute Influx of Glucose in Response to Insulin

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By Holly Dykstra, Althea N. Waldhart, Anderson S. Peck, Elissa A. Boguslawski
| Cell Press Verified
Growth Factor Stimulation Led to an Upshift in TXNIP Mobility on SDS-PAGE   Activated AKT Phosphorylated TXNIP at S308 on the Plasma Membrane   Effect of TXNIP Phosphorylation on Glucose Uptake and Phosphoinositide Interaction We have previously shown that TXNIP can be phosphorylated on S308 by AMPK under energy stress (Wu et al., 2013xAMPK-dependent degradation of TXNIP upon energy stress leads to enhanced glucose uptake via GLUT1.
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