Andrea Baragetti
As seen in:
Nature,
British Pharmacological Society,
Frontiers,
MDPI,
Taylor & Francis Online,
Cell Press
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Glucocorticoid signalling dysregulation and immune cell adaptation in Anorexia Nervosa
Abstract Anorexia Nervosa (AN) is a neuropsychiatric disorder marked by compulsive weight-loss and hyperactivity, with poorly understood underlying mechanisms and limited treatment outcomes. Here we show that women with AN, at the first medical evaluation, exhibit hyperactivity and hypercortisolemia, together with a reduced immune cell count yet paradoxically showing increased levels of cell activation.
Impact of incretin analogues on lipid and lipoprotein metabolism in obesity and diabetes
Filename Description bph70483-sup-0001-Table_S1.docxWord 2007 document , 23.5 KB Table S1.
Targeting PCSK9 beyond the liver: evidence from experimental and clinical studies
ABSTRACT Introduction PCSK9 has been widely studied as a target for lipid-lowering as its inhibition increases LDLR recycling on the surface of hepatocytes, which promotes the catabolism of LDL particles. PCSK9 can be synthesized in extra-hepatic tissues, including in the brain, the pancreas, and the heart, and in immune cells.
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