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Andrew Pham

As seen in: The New York Times, Nature, The Kitchn, BioRxiv, Cell Press, Kirkus Reviews, Brands Vietnam, EloTalk
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Articles

Sex-dependent rescue of memory and synaptic deficits in AD model mice by increasing PSD-95 palmitoylation - Communications Biology

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By Yixing Du, Katie Prinkey, Andrew Pham, Celeste Mena Morales, Maureen Dinata, Marlenne Gutierrez, Medha Sharma, Robert Rissman, Mehreen Manikkoth, Ian Baick, Haritha Karthikeyan, Kim Dore
| Nature Verified
Abstract PSD-95, a major scaffolding protein, requires palmitoylation to remain at synapses where it plays critical roles in synaptic structure and function. Here, we show that PSD-95 palmitoylation is specifically reduced in the hippocampus of female Alzheimer’s disease (AD) model mice. Accordingly, these mice have significant memory deficits that are not observed in male AD model mice.
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Piaggio Việt Nam kỷ niệm cột mốc 2 triệu xe xuất xưởng

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By Andrew Pham
| Brands Vietnam
Piaggio Việt Nam chính thức công bố cột mốc xuất xưởng chiếc xe thứ 2 triệu tại Nhà máy Piaggio Phú Thọ (trước đây thuộc tỉnh Vĩnh Phúc), đánh dấu một cột mốc quan trọng trong hành trình 18 năm phát triển của Tập đoàn Piaggio tại Việt Nam. Thành tựu này một lần nữa khẳng định vai trò chiến lược của thị trường Việt Nam với tư cách là trụ sở khu vực Châu Á – Thái Bình Dương của Tập đoàn Piaggio.
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Viral microRNA regulation of Akt is necessary for reactivation of Human Cytomegalovirus from latency in CD34+ hematopoietic progenitor cells and humanized mice

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By Nicole L. Diggins, Andrew Pham, Jennifer Mitchell, Christopher J Parkins
| BioRxiv
Abstract Human cytomegalovirus (HCMV) actively manipulates cellular signaling pathways to benefit viral replication. Phosphatidyl-inositol 3-kinase (PI3K)/Akt signaling is an important negative regulator of HCMV replication, and during lytic infection the virus utilizes pUL38 to limit Akt phosphorylation and activation. During latency, PI3K/Akt signaling also limits virus replication, but how this is overcome at the time of reactivation is unknown.
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