Angela Dramowski
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Articles by Angela Dramowski
Investigating laboratory capacity and whole genome sequencing practices to inform standardised protocols for bacterial genomic surveillance in Africa.
The authors have declared no competing interest. I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained. Yes The details of the IRB/oversight body that provided approval or exemption for the research described are given below: Ethical approval for the study was obtained from the Stellenbosch University Health Research Ethics Committee (HREC Ref no: N25/04/040).
Antibiotic stewardship and point-of-care testing for children in 25 low-income and lower-middle-income countries: a systematic review and meta-analysis
Keywords Low and lower-middle-income countries Antibiotic stewardship programs Point of care tests Antimicrobial resistance Paediatric settings Evidence before this study Antibiotics are widely used in children, and a substantial proportion are prescribed inappropriately, contributing to the global crisis of antimicrobial resistance (AMR) that is especially pronounced in resource-limited settings.
Time to recommit to saving mothers and newborns in Africa Original
Pregnancy and the newborn period (the first 28 days of life) are undoubtedly the most dangerous time in the lives of African mothers and babies, says the writer. Image by: Supplied Published 23h ago | Published 23h ago Angela Dramowski Pregnancy and the newborn period (the first 28 days of life) are undoubtedly the most dangerous time in the lives of African mothers and babies. The risk of dying in pregnancy or childbirth in Sub-Saharan Africa is 50 times higher than in high-income countries.
SafeHANDS: A Multimodal Hand Hygiene Intervention in a Resource-Limited Neonatal Unit
Open AccessArticle by Angela Dramowski 1,*, Louisa M. Erasmus 1, Marina Aucamp 2, Aaqilah Fataar 1, Mark F. Cotton 1, Susan E. Coffin 3,4, Adrie Bekker 1 and Andrew C.
Global health systems' data science approach for precision diagnosis of sepsis in early life
1. Rudd KE Johnson SC Agesa KM et al. Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study. Lancet. 2020; 395: 200-211 2. Liu L Johnson HL Cousens S et al. Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000. Lancet. 2012; 379: 2151-2161 3. Boeddha NP Schlapbach LJ Driessen GJ et al.
Impact of 1% chlorhexidine gluconate bathing and emollient application on bacterial pathogen colonization dynamics in hospitalized preterm neonates - A pilot clinical trial - EClinicalMedicine
Abstract Background Chlorhexidine gluconate (CHG) body washes and emollient application may modulate bacterial pathogen colonization and prevent neonatal hospital-acquired infections. Methods This pilot, non-randomized, open-label trial, enrolled preterm neonates (1000-1500g; day 1-3 of life) at a tertiary hospital in Cape Town, South Africa.
Intensive care unit nurses' knowledge, attitudes and practices of COVID-19 infection prevention and control
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Antimicrobial resistance among children in Africa: need for paediatric clinical trials
Simplified antibiotic regimens compared with injectable procaine benzylpenicillin plus gentamicin for treatment of neonates and young infants with clinical signs of possible serious bacterial infection when referral is not possible: a randomised, open-label, equivalence trial • • Results from a randomised clinical trial comparing equivalence of antimicrobial regimens in low resource settings in Africa.
Maverick Citizen Op-Ed: Vital to protect newborns and their mothers during the Covid-19 pandemic
Covid-19 has provided valuable lessons in infection control which will be of lasting benefit. (Photo: Hannah McKayl / Getty Images) Multiple challenges exist in preventing infection of one of our most vulnerable population groups, but Tygerberg Hospital is rising to the challenge with the implementation of policies and systems that not only mitigate the spread of coronavirus, but could also address broader infection control.
Antimicrobial resistance among children in Africa: need for paediatric clinical trials
Clinical trials are the gold standard for generating evidence-based knowledge in medicine. a disproportionately small number of clinical trials are conducted in children, a unique population who require age- and development-specific treatments. The rise in prevalence of antimicrobial resistant (AMR) – specifically antibacterial resistant – pediatric infections in both community and hospital settings in Africa [1,2] has not been matched by increases in access to effective antimicrobial therapy.
Transmission of multidrug-resistant Gram-negative bacteria from colonized mothers to their infants: a systematic review and meta-analysis
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Figure 1 Study flow diagram (PRISMA). Figure 2 Pooled proportion of MDR-GNB transmitted from colonized mothers to their infants. Figure 3 Pooled proportion of MDR-GNB transmission’s neonatal outcomes.
Essential metrics for high-quality reporting of neonatal sepsis research in low-resource settings
Although mortality in children younger than 5 years in sub-Saharan Africa has declined by 58% since 1990, neonatal deaths (in infants younger than 28 days) represent an increasing proportion, currently at 37%. , 2 UNICEF WHO World Bank Group UNLevels and trends in child mortality report. , Infection remains the third most important cause overall, and the leading cause of late neonatal deaths is hospital-acquired sepsis.
Interventions to prevent urinary catheter-associated infections in children and neonates: a systematic review
Publication HistoryPublished online: July 21, 2018Accepted: July 10, 2018; Received: May 24, 2018;
South Africa: How South Africa Can Reduce the Risk of Infections in Hospitalised Children
analysis By Angela Dramowski, Stellenbosch UniversityHealth care associated infections are infections that people acquire during their stay in hospital. Children - and babies in particular - are most at risk for hospital-acquired pneumonia, bloodstream and urinary tract infections. Children who are malnourished or living with HIV are more susceptible to these infections partly because their immune systems are compromised.
How South Africa can reduce the risk of infections in hospitalised children | IOL
These infections are the most frequent complication of health care worldwide. In America and Europe, between 4% and 5% of hospitalised children contract infections during their stay. Data from several South American countries shows that health care associated infections affect up to 6% of children. The problem is also significant in Africa. But there aren’t reliable estimates, particularly for children.
How South Africa can reduce the risk of infections in hospitalised children
Health care associated infections are infections that people acquire during their stay in hospital. Children – and babies in particular – are most at risk for hospital-acquired pneumonia, bloodstream and urinary tract infections. Children who are malnourished or living with HIV are more susceptible to these infections partly because their immune systems are compromised.
Strategies to reduce antimicrobial resistance in newborns in low-income and middle-income countries: a systematic review and meta-analysis
Introduction Antimicrobial resistance (AMR) refers to the survival of micro-organisms including bacteria, viruses, fungi, and parasites despite treatment with antimicrobial drugs, rendering these life-saving medicines ineffective.1 The mortality and economic effects of AMR cannot be overstated.
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