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Nanocarriers for Anticancer Drug Delivery: Clinical Perspectives and Translational Progress

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By Anjali Mehra, Gunjan Garg, Sresi Singh
| preprints.org
You are already at the latest version Many anticancer drugs are hydrophobic in nature. This affects the bioavailability and therapeutic efficacy of a drug to a large extent as the solubility of drug in biological system is reduced, resulting in its fast clearance from the body. Also, such drugs readily cross cell membranes and can accumulate in fatty tissues and organs.
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