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Anthony J. Ricci on Muck Rack

Anthony J. Ricci

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Articles

Auditory Hair Cell Mechanotransduction Channels Dynamically Shape the Mechanical Properties of Their Membrane Environment

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By Shefin Sam George, Anthony J. Ricci
| Wiley Online Library Verified
1 Introduction Far from being a passive envelope for cells, biological membranes form active environments that regulate the function of membrane-associated proteins.[1] Biological membranes are asymmetrical, with amine-containing phospholipids such as phosphatidylserine (PS) and phosphatidylethanolamine (PE) on the inner leaflet, while the choline-containing lipids, phosphatidylcholine (PC) and sphingomyelin (SM), are on the outer leaflet.[2, 3] This asymmetrical distribution of phospholipids...
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Dynamic modulation of auditory hair cell stereocilia membrane mechanics by the scrambling mechanotransduction complex

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By Shefin Sam George, Anthony J. Ricci
| BioRxiv
Abstract Inner ear sensory hair cells convert mechanical deflection of their hair bundle into an electrical signal by gating novel mechanoelectrical transduction (MET) channels. Transmembrane channel-like proteins (TMCs) are a component of the MET machinery and part of a superfamily of molecules whose members are ion channels or lipid scramblases.
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The Cousa objective: a long-working distance air objective for multiphoton imaging in vivo - Nature Methods

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By Che-Hang Yu, Yiyi Yu, Jeremy T. Chang, Brent Young, Austin Leikvoll, Rachel Vistein, Santiago Otero-Coronel, Alipasha Vaziri, Jeffrey Goldberg Verified, Anthony J. Ricci, Jessica A. Cardin, Michael J. Higley, Gordon Smith, Kristina J. Nielsen
| Nature Verified
Abstract Multiphoton microscopy can resolve fluorescent structures and dynamics deep in scattering tissue and has transformed neural imaging, but applying this technique in vivo can be limited by the mechanical and optical constraints of conventional objectives. Short working distance objectives can collide with compact surgical windows or other instrumentation and preclude imaging. Here we present an ultra-long working distance (20 mm) air objective called the Cousa objective.
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