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The art of decorating piperidine scaffold into alkaloid precursors
The saturated six-membered N-heterocycle, also referred as the piperidine scaffold: is the most representative organic skeleton in small-molecule drugs approved by the U.S. FDA [[1], [1]a), [1]b)]. Consequently, it is one of the most common substrate for the design of drugs and agrochemicals. [[1], [1]c)].
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