Aritsara Jaruwat on Muck Rack

Aritsara Jaruwat

As seen in: The Journal of Biological Chemistry
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Articles

Structural Insights into a Flavin-dependent Dehalogenase HadA Explain Catalysis and Substrate Inhibition via Quadruple π-stacking

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By Panu Pimviriyakul, Aritsara Jaruwat, Phahonyothin Road, Penchit Chitnumsub
| The Journal of Biological Chemistry Verified
Abstract HadA is a flavin-dependent monooxygenase catalyzing hydroxylation plus dehalogenation/denitration which is useful for biodetoxification and bio-detection. In this study, the X-ray structure of wild-type HadA (HadAWT) co-complexed with reduced FAD (FADH–) and 4-nitrophenol (4NP) (HadAWT−FADH–−4NP) was solved at 2.3 Å resolution, providing the first full package (with flavin and substrate bound) structure of a monooxygenase of this type.
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Dissecting the low catalytic capability of flavin-dependent halogenases

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By Narin Lawan, Aisaraphon Phintha, Kridsadakorn Prakinee, Aritsara Jaruwat
| The Journal of Biological Chemistry Verified
Aisaraphon Phintha1, Kridsadakorn Prakinee2, Aritsara Jaruwat3, Narin Lawan4, Surawit Visitsatthawong5, Chadaporn Kantiwiriyawanitch5, Warangkhana Songsungthong3, Duangthip Trisrivirat1, Pirom Chenprakhon1, Adrian J.
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