Áron Bartha
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UbiDash: A UPS proteomic atlas for tissue-aware degrader design
Abstract Targeted protein degradation repurposes endogenous E3 ubiquitin ligases to eliminate disease-driving proteins, yet the ligase toolkit deployed clinically remains narrow and largely tissue-agnostic.
TNMplot: An enhanced platform for pharmacological target identification through cross-stage and pan-cancer gene expression analysis
AJCC American Joint Committee on Cancer CRC colorectal carcinoma EZH2 enhancer of zeste homologue 2 GEO gene expression omnibus GTEx genotype-tissue expression MET mesenchymal-epithelial transition factor NSCLC non-small cell lung cancer 1 INTRODUCTION We previously established TNMplot.com, a web-based tool for the comparison of gene expression from tumour, normal and metastatic (TNM) samples by employing RNA-seq and gene-chip-based datasets (Bartha & Győrffy, 2021).
Melanoma Proteomics Unveiled: Harmonizing Diverse Data Sets for Biomarker Discovery and Clinical Insights via MEL-PLOT
Special Issue Published as part of Journal of Proteome Research special issue “Software Tools and Resources 2025”. Introduction Click to copy section linkSection link copied! Proteins are the primary actors in biological molecular events, and they play a crucial role as biomarkers for diagnosing and estimating the prognosis of diseases and common targets for therapeutic interventions.
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