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Ascencion Torres-Escobar

As seen in: BioRxiv
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Articles

A nutritional immunity blockade controls extracellular bacterial replication in Legionella pneumophila infections.

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By Ascencion Torres-Escobar, Ashley Wilkins, Maria D. Juarez-Rodriguez, Magdalena Circu
| BioRxiv
Abstract The accidental human pathogen Legionella pneumophila (Lp) is the etiological agent for a severe atypical pneumonia known as Legionnaires′ disease. In human infections and animal models of disease alveolar macrophages are the primary cellular niche that supports bacterial replication within a unique intracellular membrane–bound organelle.
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The intracellular growth of the vacuolar pathogen Legionella pneumophila is dependent on the acyl chain composition of host membranes

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By Ashley Wilkins, Benjamin Schwarz, Ascencion Torres-Escobar, Reneau Castore
| BioRxiv
Abstract Legionella pneumophila is an accidental human bacterial pathogen that infects and replicates within alveolar macrophages causing a severe atypical pneumonia known as Legionnaires disease. As a prototypical vacuolar pathogen L. pneumophila establishes a unique endoplasmic reticulum (ER)—derived organelle within which bacterial replication takes place.
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