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Astar Shamul-Raybi on Muck Rack

Astar Shamul-Raybi

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Articles

Computational design of optimized and preferentially paired human TCR constant regions for improved T cell function

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By Pushpamali De Silva, Nathan Burton, Maria Radman, Jake Parker, Sarel J. Fleishman, Cyrille J. Cohen, Astar Shamul-Raybi
| Science Magazine Verified
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share This article has 0 eLetter . Abstract T cell receptor (TCR) gene transfer is a promising approach for cancer immunotherapy, but its efficacy is limited by mispairing of TCR chains, which reduces surface expression and may generate off-target specificities.
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