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The Emerging Role of Dimethyl Fumarate in Alzheimer’s Disease-A Systematic Review of Available Preclinical Studies[v1]
This open access article is published under a , which permit the free download, distribution, and reuse, provided that the author and preprint are cited in any reuse.
A systematic review and meta-analysis of tau phosphorylation in mouse models of familial Alzheimer's disease
Abstract Background: Transgenic models of familial Alzheimer's disease (AD) serve as valuable tools for probing the molecular mechanisms associated with amyloid-beta (Aβ)-induced pathology. Here, we sought to evaluate the levels of phosphorylated tau (p-tau) protein, and explore potential age-related variations in the hyperphosphorylation of tau, in mouse models of cerebral amyloidosis.
Epigenetic regulation of synaptic disorder in Alzheimer’s disease
Introduction Alzheimer’s disease (AD) is a degenerative disease of the central nervous system characterized by progressive cognitive and behavioral impairment, which seriously affects the quality of life of the elderly (Shah et al., 2016; Chhatwal et al., 2022). AD is caused by complex interactions between genetic and environmental factors and lacks effective treatment measures.
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