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Azra C Ghani on Muck Rack

Azra C Ghani

As seen in: Financial Times, Nature, The Guardian, PLOS Medicine, New Scientist, BioRxiv, The Lancet, Observador, Emerald Publishing
Infectious disease epidemiologist & mathematical modeller focusing on eliminating malaria @ImperialMalaria
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Articles

Global risk of selection and spread of Plasmodium falciparum histidine-rich protein 2 and 3 gene deletions - Nature Medicine

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By Oliver Watson, Robert J. Zupko, Paulina A. Dzianach, Isaac Kim, Jonathan J. Juliano, Jeffrey Bailey, Hannah C. Slater, Lucy C Okell, Azra C Ghani, Maciej F. Boni, Jonathan Parr, Tasmin Symons
| Nature Verified
Abstract Since their first detection in 2010, Plasmodium falciparum malaria parasites lacking the P. falciparum histidine-rich protein 2 gene (pfhrp2) have been observed in 40 of 47 surveyed countries, as documented by the World Health Organization. These genetic deletions reduce detection by the most widely used rapid diagnostic tests, prompting three countries to switch to alternative diagnostics.
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What's next in the fight against malaria?

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By Azra C Ghani
| New Scientist Verified
Malaria is one of humanity’s oldest killers, with records of cases dating back to ancient Egypt. But despite efforts to eradicate the disease, a new report from the World Health Organization estimates that nearly 600,000 people died of malaria in 2023, most of whom were children. Progress in reducing the number of deaths has stagnated, with malaria cases increasing since 2018 because of a perfect storm of challenges.
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The potential of gene drives in malaria vector species to control malaria in African environments - Nature Communications

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By Penelope A. Hancock, Adrian Leach, Peter Winskill, Azra C Ghani, Austin Burt
| Nature Verified
Abstract Gene drives are a promising means of malaria control with the potential to cause sustained reductions in transmission. In real environments, however, their impacts will depend on local ecological and epidemiological factors. We develop a data-driven model to investigate the impacts of gene drives that causes vector population suppression.
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