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Bálint A. Barta on Muck Rack

Bálint A. Barta

As seen in: Color Research & Application, BioRxiv
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Articles

The COVID-19 mRNA vaccine Comirnaty induces anaphylactic shock in an anti-PEG hyperimmune large animal model: Role of complement in cardiovascular, hematological, and inflammatory mediator changes

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By Bálint A. Barta, Tamás Radovits, Attila B. Dobos, Gergely T. Kozma
| BioRxiv
Abstract Background: Comirnaty, Pfizer-BioNTech's polyethylene-glycol (PEG)-containing Covid-19 vaccine, can cause hypersensitivity reactions (HSRs) in a small fraction of immunized people which can, very rarely, culminate in life-threatening anaphylaxis. A role of anti-PEG antibodies (Abs) has been proposed, but causality has not yet been proven in an animal model. This study aimed to provide such evidence using anti-PEG hyperimmune pigs (i.e., pigs displaying very high levels of anti-PEG Abs).
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Prevention of the development of heart failure with preserved ejection fraction by the phosphodiesterase-5A inhibitor vardenafil in rats with type 2 diabetes - Mátyás - 2016 - European Journal of Heart Failure - Wiley Online Library

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By Attila Oláh, Gabor Szabo, Zoltán Papp, Béla Merkely, Csaba Mátyás, Balázs T. Németh, Marianna Török, Mihály Ruppert, Dalma Kellermayer, Bálint A. Barta, Eszter M. Horváth, Beáta Bódi, Tamás Radovits
| Color Research & Application Verified
Heart failure with preserved ejection fraction (HFpEF) has a great epidemiological burden. The pathophysiological role of cyclic guanosine monophosphate (cGMP) signalling has been intensively investigated in HFpEF. Elevated levels of cGMP have been shown to exert cardioprotective effects in various cardiovascular diseases, including diabetic cardiomyopathy.
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