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Barbara G. Mellone on Muck Rack

Barbara G. Mellone

As seen in: BioRxiv, Cell Press
Professor @UConnMCB studying centromeres, chromosomes & transposons in Drosophila | She/Her | Opinions my own | @centromellone.bsky.social
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Articles

A centromere-derived retroelement RNA localizes in cis and is a core element of the transcriptional landscape of Drosophila centromeres

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By Barbara G. Mellone, Bryce Santinello, Ruiyi Sun, Asna Amjad
| BioRxiv
Abstract Centromeres are essential chromosomal landmarks that dictate the point of attachment between chromosomes and spindle microtubules during cell division. The stable transmission of the centromere site through generations is ensured by a unique chromatin containing the histone H3 variant CENP-A. Previous studies have highlighted the impact of transcription on promoting CENP-A deposition.
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Diverse mechanisms of centromere specification

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By Daniele Fachinetti, Barbara G. Mellone
| Cell Press Verified
Santaguida S. Musacchio A. The life and miracles of kinetochores. EMBO J. 2009; 28: 2511-2531 Santaguida S. Amon A. Short- and long-term effects of chromosome mis-segregation and aneuploidy. Nat. Rev. Mol. Cell Biol. 2015; 16: 473-485 Murillo-Pineda M. Jansen L.E.T. Genetics, epigenetics and back again: Lessons learned from neocentromeres. Exp. Cell Res. 2020; 389: 111909 Sullivan L.L. Sullivan B.A. Genomic and functional variation of human centromeres. Exp. Cell Res.
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