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Barbara Haigl on Muck Rack

Barbara Haigl

As seen in: JoVE- Journal of Visualized Experiments, Atherosclerosis
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Articles

Ikk2-mediated inflammatory activation of arterial endothelial cells promotes the development and progression of atherosclerosis

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By Marion Mussbacher, Barbara Haigl, Manuel Salzmann, José Basílio
| Atherosclerosis Verified
Highlights • Inflammatory activation of endothelial cells via a constitutively active form of IKK2 in ApoE −/− mice. • Inflammatory endothelial activation aggravated atherosclerosis at early and late stages. • Endothelial-cell specific inflammation caused phenotypic transitions of smooth-muscle cells. Abstract Background and aims Inflammatory activation of endothelial cells is considered to be the first step in the development of atherosclerosis.
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A Laser Capture Microdissection Protocol That Yields High Quality RNA from Fresh-frozen Mouse Bones

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By Ana Marek, Barbara Haigl, Reinhold G. Erben
| JoVE- Journal of Visualized Experiments
Biology Fill out the form below to receive a free trial or learn more about access: Unable to load video. Please check your Internet connection and reload this page. If the problem continues, please let us know and we'll try to help. An unexpected error occurred. Please check your Internet connection and reload this page. If the problem continues, please let us know and we'll try to help.
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MicroRNA-21 Increases Proliferation and Cisplatin Sensitivity of Osteosarcoma-Derived Cells

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By Vanita Vanas, Barbara Haigl, Verena Stockhammer, Hedwig Sutterlüty-Fall
| PLOS
Osteosarcoma is the most common primary bone tumor and poor prognosis for osteosarcoma patients is mainly due to chemotherapy resistance. MicroRNAs are important to maintain pathophysiological mechanisms of cancer and influence cell sensitivity to chemotherapy. In this study, we tested the functions of microRNA-21 for malignant features as well as for drug resistance of osteosarcoma. We used Northern blot to measure microRNA-21 levels in osteosarcoma-derived cell lines.
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