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Barbara Hanson on Muck Rack

Barbara Hanson

As seen in: Neurology, The Journal of Clinical Investigation, The News-Star
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Articles

Human pegivirus alters brain and blood immune and transcriptomic profiles of patients with Parkinson’s disease

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By JCI Insight, Barbara Hanson, Xin Dang, Pouya Jamshidi
| The Journal of Clinical Investigation
Abstract Parkinson’s disease (PD) is a neurodegenerative disorder with both genetic and environmental factors contributing to pathogenesis. Viral infections are potential environmental triggers that influence PD pathology. Using ViroFind, an unbiased platform for whole virome sequencing, along with quantitative PCR (qPCR), we identified human pegivirus (HPgV) in 5 of 10 (50%) of PD brains, confirmed by IHC in 2 of 2 cases, suggesting an association with PD.
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T cell responses to SARS-CoV-2 in people with and without neurologic symptoms of long COVID

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By Lavanya Visvabharathy, Barbara Hanson, Zachary S Orban, Patrick H. Lim
| medRxiv
Abstract Many people experiencing long COVID syndrome, or post-acute sequelae of SARS-CoV-2 infection (PASC), suffer from debilitating neurologic symptoms (Neuro-PASC). However, whether virus-specific adaptive immunity is affected in Neuro-PASC patients remains poorly understood.
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Plasma Biomarkers of Neuropathogenesis in Hospitalized Patients With COVID-19 and Those With Postacute Sequelae of SARS-CoV-2 Infection

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By Barbara Hanson, Lavanya Visvabharathy, Sareen T. Ali, Anthony K. Kang
| Neurology Verified
Abstract Background and Objectives Although patients hospitalized with COVID-19 frequently present with encephalopathy, those with mild initial COVID-19 disease who never required hospitalization also often develop neurologic symptoms as part of postacute sequelae of severe acute respiratory coronavirus type 2 (SARS-CoV-2) infection (neuro-PASC). The pathogenic mechanisms of COVID-19 encephalopathy and neuro-PASC are unknown.
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