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Structural and functional analysis of the Nipah virus polymerase complex
Keywords Nipah virus RNA virus polymerase emerging viruses RNA replication RNA transcription Introduction Nipah virus (NiV) is an enveloped RNA virus in the family Paramyxoviridae of the order Mononegavirales, the non-segmented negative-strand RNA viruses (nsNSVs).1 In humans, NiV infection can lead to respiratory illness or encephalitis with a fatality rate ranging from 40% to 70%.2 Since the identification of NiV in Malaysia in 1998, spillover events from bats into humans have occurred...
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