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Barbara R Tschida on Muck Rack

Barbara R Tschida

As seen in: JHEP Reports
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Articles

ZBTB20 regulates WNT/CTNNB1 signalling pathway by suppressing PPARG during hepatocellular carcinoma tumourigenesis

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By Jeffrey To, Hung Hom, Amy P. Chiu, Barbara R Tschida
| JHEP Reports Verified
Highlights • Zbtb20 was identified as a candidate liver cancer gene by both forward and reverse genetics. • ZBTB20 promotes HCC tumorigenesis by suppressing PPARG expression • This results in activation of the WNT/CTNNB1 signalling pathway. Background & Aims Zinc finger and BTB domain containing 20 (ZBTB20) has been implicated as a potential oncogene in liver cancer.
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Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic Tumors

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By Barbara R Tschida, Nuri A. Temiz, Timothy P Kuka, Lindsey Lee
| cancerres.aacrjournals.org
Molecular and Cellular Pathobiology Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic Tumors Barbara R. Tschida, Nuri A. Temiz, Timothy P. Kuka, Lindsey A. Lee, Jesse D. Riordan, Carlos A. Tierrablanca, Robert Hullsiek, Sandra Wagner, Wendy A. Hudson, Michael A. Linden, Khalid Amin, Pauline J. Beckmann, Rachel A. Heuer, Aaron L. Sarver, Ju Dong Yang, Lewis R. Roberts, Joseph H. Nadeau, Adam J. Dupuy, Vincent W. Keng and David A. Largaespada
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Sleeping Beauty insertional mutagenesis in mice identifies drivers of steatosis-associated hepatic tumor

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By Nuri A. Temiz, Lindsey Lee, Barbara R Tschida, Timothy P Kuka
| cancerres.aacrjournals.org
Sleeping Beauty insertional mutagenesis in mice identifies drivers of steatosis-associated hepatic tumor Barbara R Tschida, Nuri A. Temiz, Timothy P Kuka, Lindsey A Lee, Jesse D Riordan, Carlos A Tierrablanca, Robert Hullsiek, Sandra Wagner, Wendy A Hudson, Michael A Linden, Khalid Amin, Pauline J Beckmann, Rachel A Heuer, Aaron L. Sarver, Ju Dong Yang, Lewis R. Roberts, Joseph H. Nadeau, Adam J Dupuy, Vincent W. Keng and David Largaespada Cancer Res October 9 2017 DOI: 10.1158/0008-5472.CAN-17-2281
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