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Barbara Tabak

As seen in: Cell Press
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Articles

Higher-Order Inter-chromosomal Hubs Shape 3D Genome Organization in the Nucleus

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By Sofia A Quinodoz, Noah Ollikainen, Barbara Tabak, Ali Palla
| Cell Press Verified
Eukaryotic genomes are packaged into a 3-dimensional structure in the nucleus. Current methods for studying genome-wide structure are based on proximity ligation. However, this approach can fail to detect known structures, such as interactions with nuclear bodies, because these DNA regions can be too far apart to directly ligate. Accordingly, our overall understanding of genome organization remains incomplete.
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Higher-order inter-chromosomal hubs shape 3-dimensional genome organization in the nucleus

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By Sofia A Quinodoz, Noah Ollikainen, Barbara Tabak, Ali Palla
| BioRxiv
Higher-order inter-chromosomal hubs shape 3-dimensional genome organization in the nucleus Sofia A Quinodoz, Noah Ollikainen, Barbara Tabak, Ali Palla, Jan Marten Schmidt, Elizabeth Detmar, Mason Lai, Alexander Shishkin, Prashant Bhat, Vickie Trinh, Erik Aznauryan, Pamela Russell, Christine Cheng, Marko Jovanovic, Amy Chow, Patrick McDonel, Manuel Garber, Mitchell Guttman bioRxiv 219683; doi: https://doi.org/10.1101/219683
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