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Barbara Tolusso

As seen in: Color Research & Application, Nature, Wiley, Wiley Online Library, Annals of the Rheumatic Diseases, Educational Studies, MDPI, Arthritis Research & Therapy, Expert Review of Anticancer Therapy, Cell Press
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Articles

Synovial tissue myeloid dendritic cell subsets exhibit distinct tissue-niche localization and function in health and rheumatoid arthritis

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By Lucy Macdonald, Aziza Elmesmari, Domenico Somma, Jack Frew, Clara Di Mario, Roopa Madhu, Audrey Paoletti, Theodoros Simakou, Olympia Hardy, Barbara Tolusso, Simone Perniola, Marco Gessi, Maria Rita Gigante, Luca Petricca, Dario Bruno, Lavinia Agra Coletto, Roberta Benvenuto, John D Isaacs, Andrew Filby, David McDonald, Nigel Jamieson, Kevin HC Wei, Maria Antonietta D’agostino, Neal L. Millar, Simon Milling, Charles Mcsharry, Elisa Gremese, Karen Affleck, Kenneth Baker, Iain B McInnes, Thomas D. Otto, Ilya Korsunsky, Stefano Alivernini, Mariola Kurowska-Stolarska, Denise Campobasso, Jasmine P.X. Sim
| Cell Press Verified
Keywords immune tolerance arthritis disease remission dendritic cells synovial tissue spatial transcriptomics T cells Introduction Rheumatoid arthritis (RA) is an inflammatory joint disease with systemic comorbidities, driven by the breach of immune tolerance.1 Advances in targeted therapies2 have transformed the management of RA.
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IJMS | Free Full-Text | B-Cell Activation Biomarkers in Salivary Glands Are Related to Lymphomagenesis in Primary Sjögren’s Disease: A Pilot Monocentric Exploratory Study

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By Dario Bruno, Barbara Tolusso, Gianmarco Lugli, Clara Di Mario
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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COVID‐19 illness: Different comorbidities may require different immunological therapeutic targets

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By Elisa Gremese, Barbara Tolusso, Dario Bruno, Anna Maria Paglionico
| Wiley Online Library Verified
Evidence before this study Uncontrolled studies showed some clinical benefit in different cohorts of severe-critical COVID-19 pneumonia, through targeting IL6, IL1 or GM-CSF. The SARS-CoV-2-induced cytokine release syndrome (CRS) is different from chimeric antigen receptor-modified T (CAR-T) cell therapy-associated one, in which IL6 and IL1 are the main players, while high plasma levels of IL6, IL8, GM-CSF, IL-10 and others have been demonstrated in SARS-CoV-2-induced CRS.
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