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Barbara Trifault on Muck Rack

Barbara Trifault

As seen in: BioRxiv, Genes and Development Journal
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Articles

NEAT1 promotes genome stability via m6A methylation-dependent regulation of CHD4

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By Victoria Mamontova, Barbara Trifault, Anne-Sophie Gribling-Burrer, Patrick Bohn
| Genes and Development Journal
1,2 1Mildred Scheel Early Career Center for Cancer Research (Mildred-Scheel-Nachwuchszentrum [MSNZ]) Würzburg, University Hospital Würzburg, 97080 Würzburg, Germany; 2Department of Biochemistry and Molecular Biology, Biocenter of the University of Würzburg, 97074 Würzburg, Germany; 3Helmholtz Institute for RNA-Based Infection Research, Helmholtz-Center for Infection Research, 97808 Würzburg, Germany; 4Department of RNA Biology and Pathogenesis, Institute of Molecular Medicine, Martin Luther...
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NEAT1 promotes genome stability via m6A methylation-dependent regulation of CHD4

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By Victoria Mamontova, Barbara Trifault, Patrick Bohn, Anne-Sophie Gribling-Burrer
| BioRxiv
Abstract Long non-coding (lnc)RNA emerge as regulators of genome stability. The nuclear enriched abundant transcript 1 (NEAT1) locus encodes two lncRNA isoforms that modulate gene expression, growth and proliferation in mammals. Interestingly, NEAT1 transcripts are overexpressed in many tumours and induced by DNA damage, suggesting a genome-protective function. However, the precise role of NEAT1 in the DNA damage response (DDR) is unclear.
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Nucleolar detention of NONO shields DNA double-strand breaks from aberrant transcripts

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By Giacomo Cossa, Barbara Trifault, Victoria Mamontova, Sabina Ganskih
| BioRxiv
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