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Barbara Walzog on Muck Rack

Barbara Walzog

As seen in: Nature, Wiley Online Library, The Journal of Immunology
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Articles

Mutations in VPS18 lead to a neutrophil maturation defect associated with disturbed vesicle homeostasis - Cell Death & Disease

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By Jincheng Gao, Almke Bader, Mathis Richter, Felix Meissner, Stephanie Frenz-Wiessner, Oliver Soehnlein, Barbara Walzog, Karl Mitt
| Nature Verified
Abstract Neutrophils, the first cells to arrive at the site of inflammation, are rather short-lived cells and thus have to be constantly replenished. During neutrophil development, vesicle dynamics need to be fine-tuned and impaired vesicle trafficking has been linked to failure in neutrophil maturation. Here, we characterized the role of VPS18 as a central core component of CORVET & HOPS tethering complexes for neutrophil development.
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Plasmacytoid dendritic cells control homeostasis of megakaryopoiesis - Nature

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By Florian Gaertner, Hellen Ishikawa-Ankerhold, Anne Dueck, Valeria Fumagalli, Alejandro Navarro Verified, Louisa von Baumgarten, Tobias Straub, Vanessa Zheden, Saskia von Stillfried, Peter Boor, Marco Colonna, Christian Schulz, Thomas Bröcker, Barbara Walzog, Christoph Scheiermann, Claus Nerlov, Stefan Engelhardt, Robert Hauschild, Matteo Iannacone, Matthias Heinig, Jan Kranich, Sebastian Clauß
| Nature Verified
Abstract Platelet homeostasis is essential for vascular integrity and immune defence1,2. Although the process of platelet formation by fragmenting megakaryocytes (MKs; thrombopoiesis) has been extensively studied, the cellular and molecular mechanisms required to constantly replenish the pool of MKs by their progenitor cells (megakaryopoiesis) remains unclear3,4. Here we use intravital imaging to track the cellular dynamics of megakaryopoiesis over days.
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Author Correction: Vascular surveillance by haptotactic blood platelets in inflammation and infection - Nature Communications

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By Leo Nicolai, Alexander Leunig, Kami Pekayvaz, Achim Löf, Barbara Walzog, Christian Schulz, Markus Bender, Rong Li, Florian Gaertner
| Nature Verified
Correction to: Nature Communications https://doi.org/10.1038/s41467-020-19515-0, published online 13 November 2020. The original version of this Article contained an error in the “Introduction”, as reference was missing. The original version read incorrectly “[…] since the abrogation of lamellipodia formation does not affect hemostatic or thrombotic platelet functions 22,23 […]”.
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