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Increase in calcidiol level is associated with improved sternal bone healing after cardiac surgery with sternotomy—REINFORCE-D trial results - Trials
This prospective, randomized, double-blind trial opened new point of view to the cardiac surgery with sternotomy risk factors and their individualized prevention. Since the trial began, there have been other trials concerned with the same topic [14, 15]. One trial by radiology specialists from Turkey was very similarly designed [16]. They observed subjects in cohorts with different calcidiol deficiencies and examined them by CT after 3 and 6 months.
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