Barbra Dickerman
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The TARGET guideline for reporting observational studies of interventions
Observational (non-experimental) studies of interventions can generate valuable evidence when randomized trials are infeasible, unethical or unable to provide timely answers to important clinical and policy questions. The use of observational data to estimate the comparative benefits and harms of medical interventions has increased substantially and has informed clinical, policy and regulatory decisions1,2.
Comparative effectiveness of third doses of mRNA-based COVID-19 vaccines in US veterans - Nature Microbiology
Abstract Vaccination against SARS-CoV-2 has been effective in reducing the burden of severe disease and death from COVID-19. Third doses of mRNA-based vaccines have provided a way to address waning immunity and broaden protection against emerging SARS-CoV-2 variants. However, their comparative effectiveness for a range of COVID-19 outcomes across diverse populations is unknown.
Comparative Safety of BNT162b2 and mRNA-1273 Vaccines in a Nationwide Cohort of US Veterans
Comparative Safety of BNT162b2 and mRNA-1273 Vaccines in a Nationwide Cohort of US Veterans | Vaccination | JAMA Internal Medicine | JAMA Network [Skip to Navigation] Figure. Selection of Persons for the Emulation of a Target Trial Evaluating the Comparative Safety of the BNT162b2 and mRNA-1273 Vaccines (January 4 to October 5, 2021) BMI indicates body mass index; VA, US Department of Veterans Affairs. Table 1.
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