We present the TARGET checklist alongside additional information for items. Details on the rationale for and interpretation of each item, and examples of reporting, will be provided in a separate explanation and elaboration document. Checklist items are grouped according to the typical structure of original investigations reporting research results: abstract (item 1), introduction (items 2-4), methods (items 5-7), results (items 8-14), discussion (items 15-16), and other information (items 17-21).