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Treatment options to support the elimination of hepatitis C: an open-label, factorial, randomised controlled non-inferiority trial
Introduction The development of direct-acting antivirals for hepatitis C virus (HCV) infection has transformed individual treatment and underpins ambitious WHO targets for global elimination of viral hepatitis as a public health threat by 2030.1 Of three WHO-recommended pan-genotypic first-line treatment options, two are preferred by lower-income and lower-middle-income countries and are available from generic manufacturers: sofosbuvir–daclatasvir and sofosbuvir–velpatasvir.2 No randomised...
Treatment options to support the elimination of hepatitis C: an open-label, factorial, randomised controlled non-inferiority trial
Introduction The development of direct-acting antivirals for hepatitis C virus (HCV) infection has transformed individual treatment and underpins ambitious WHO targets for global elimination of viral hepatitis as a public health threat by 2030.1 Of three WHO-recommended pan-genotypic first-line treatment options, two are preferred by lower-income and lower-middle-income countries and are available from generic manufacturers: sofosbuvir–daclatasvir and sofosbuvir–velpatasvir.2 No randomised...
Progress towards elimination of viral hepatitis: a Lancet Gastroenterology & Hepatology Commission update
1. Cooke GS Andrieux-Meyer I Applegate TL et al. Accelerating the elimination of viral hepatitis: a Lancet Gastroenterology & Hepatology Commission. Lancet Gastroenterol Hepatol. 2019; 4: 135-184 2. Ward JW Wiktor SZ Cooke GS Launch of the Coalition for Global Hepatitis Elimination: a recommendation of the Lancet Gastroenterology & Hepatology Commission. Lancet Gastroenterol Hepatol. 2020; 5: 8-10 3.
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