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Barnstable Brown Diabetes

As seen in: Wiley Online Library, Frontiers, Diabetes Spectrum
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Articles

Editorial: Metabolic and biomechanical factors in bone fragility: new frontiers in understanding and managing osteoporosis

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By Barnstable Brown Diabetes
| Frontiers
Skeletal fragility results primarily from loss of bone mass or changing structure that diminish bone quality and strength. Osteoporosis can be classified as primary or secondary, depending on the underlying factors that lead to loss of bone mass, deterioration of microarchitecture or compromised bone metabolism.
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Lrtm1 - A Novel Sensor of Insulin Signaling and Regulator of Metabolism and Activity

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By Barnstable Brown Diabetes, C. Ronald, Vitor Rosetto
| Diabetes Spectrum
Insulin regulates glucose uptake and metabolism in muscle via the insulin receptor. Here we show that Lrtm1 (Leucine Rich Repeats and Transmembrane Domains 1), a protein of unknown function enriched in insulin-responsive metabolic tissues, senses changes in insulin signaling in muscle and serves as a regulator of metabolic response.
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T cells in obesity‐associated inflammation: The devil is in the details

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By Yolander A. Valentine, Barbara S Nikolajczyk, Barnstable Brown Diabetes
| Wiley Online Library Verified
CONFLICT OF INTEREST STATEMENT The authors have no conflict of interest. REFERENCES 1. What is obesity?: definition as a disease, with implications for care. Gastroenterol Clin N Am. 2023; 52(2): 261-275. 2, , , . Obesity: pathophysiology and management. J Am Coll Cardiol. 2018; 71(1): 69-84. 3, , , , , . New obesity classification criteria as a tool for bariatric surgery indication. World J Gastroenterol. 2016; 22(2): 681-703. 4, , , et al. The relationship between obesity and other medical comorbidities.
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