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Barry A. Badeau on Muck Rack

Barry A. Badeau

As seen in: AIChE Journal, Nature, BioRxiv
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Articles

Dual activation of MC3R and MC4R drives weight loss and reduces food intake in male primates with obesity

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By Jillian L. Seiler, Anna Impastato, Kade Kelley, Thomas Bennett, Bradley Studnitzer, Claudia R. Prindle, Benjamin Rajewski, Barry A. Badeau, Xinjian Jiang, Russell Potterfield, Jordan Y. Delev, Daniel Marks
| Nature Verified
Abstract The melanocortin system plays a central role in regulating hunger and satiety, making it an attractive target for treating metabolic disease. However, the limited clinical success of selective melanocortin-4 receptor (MC4R) agonists has prompted investigation into whether concurrent melanocortin-3 receptor (MC3R) and MC4R activation may more effectively engage this pathway for the treatment of general obesity.
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117548-22-8，5(6)-FAM, SE相关的化学性质介绍

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By Barry A. Badeau, Ying Zheng, Cole A. DeForest, L Marcus Wilhelmsson
| bilibili.com
物理参数： 英文名称：5(6)-FAM, SE，5(6)-Carboxyfluorescein N-hydroxysuccinimide ester，5(6)-Carboxyfluorescein N-hydroxysuccinimide ester 中文名称：5(6)-羧基荧光素琥珀酰亚胺酯 CAS：117548-22-8 分子式：C25H15NO9 分子量：473.39 外观：红色固体 溶剂：DMSO 激发波长（nm）：494 发射波长（nm）：519 性状：固体或液体（根据分子量决定） 规格标准：1g，5g，10g 储存条件：-20℃，干燥，避免频繁解冻和冷冻 产品可定制：根据需要的试剂进行定制，具体的可以线上和商家沟通 品牌名称：西安凯新生物科技有限公司 结构式： 简述： 5(6)-FAM,SE（5(6)-羧基荧光素琥珀酰亚胺酯） (117548-22-8)是一种绿色荧光染料，广泛应用于蛋白质标记。 光谱图： 参考文献： Multicellular Vascularized Engineered Tissues through User-Programmable...
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Versatile tissue‐injectable hydrogels capable of the extended hydrolytic release of bioactive protein therapeutics

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By Eric S Nealy, Steven J. Reed, Steven M Adelmund, Barry A. Badeau
| AIChE Journal Verified
We have developed injectable hydrogels for local, controlled release of protein therapeutics into tissue, particularly beneficial for potent immunotherapies with severe systemic toxicities. The hydrogel, featuring slowly hydrolyzing linkers, prolongs the therapeutic effect, minimizing the requirement for repeated surgeries.
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