Barry Paul
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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
Precision Medicine with Duvelisib and the Evolving Landscape of Lymphoma
The treatment landscape for peripheral T-cell lymphoma (PTCL) is currently defined by a critical paradox: while our understanding of the disease’s biological heterogeneity is expanding rapidly, the clinical toolkit remains frustratingly limited. For years, a "one-size-fits-all" chemotherapy approach has served as the backbone of care, yet many patients do not experience durable remissions.
119 Progression-Free Survival (PFS) and Overall Survival (OS) Results From the Phase 3 MONALEESA-3 Trial of Postmenopausal Patients With Hormone Receptor–Positive (HR+)/Human Epidermal Growth Factor Receptor 2–Negative (HER2−) Advanced Breast Cancer (ABC)
Background MONALEESA-3 reported statistically significant overall survival (OS) benefits with ribociclib plus fulvestrant, which were maintained with extended follow-up. Patients with invasive lobular carcinoma (ILC) subtype, 10% to 15% of breast cancer cases, show unique clinicopathological characteristics. This exploratory analysis examined progression-free survival (PFS), OS, response rates, and safety in patients with ILC in MONALEESA-3, including those receiving first-line treatment.
What is the Future of TIL Therapy in Metastatic Melanoma?
The landscape of metastatic melanoma treatment is shifting toward more personalized, cellular-based approaches. In this interview clip, Muhammad Umair Mushtaq, MD, associate professor of medicine in the Division of Hematologic Malignancies and Cellular Therapeutics at the University of Kansas Medical Center, highlighted why the timing of treatment is just as critical as the therapy itself.
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