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Bart Boets

As seen in: Color Research & Application, Nature, Wiley Online Library, MDPI, BioRxiv, Cell Press, JNeurosci
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Articles

Effects of chronic oxytocin administration on white matter microstructure in autistic adults: a pilot pharmaco-neuroimaging DTI study

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By Robin Emily Heemels, Bart Boets, Kaat Alaerts, Ward Deferm
| Nature Verified
Abstract Intranasal oxytocin is a promising therapeutic approach for social and stress-regulatory difficulties in autism spectrum disorder. However, there is limited understanding regarding whether chronic administration regimes can induce neuroplastic changes at the brain’s anatomical level and how such microstructural changes might underlie clinical-behavioral effects.
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Heart rate variability after hospital discharge in perinatal risk populations: a systematic review and meta-analysis

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By Lisa Gistelinck, Rowena Van den Broeck, Maarten de Vos, Sam V. Wass, Gunnar Naulaers, Bart Boets, Cato Verhelst
| Nature Verified
Abstract Perinatal risk factors such as preterm birth, intrauterine growth restriction, and low birth weight are linked to elevated cardiovascular and neurodevelopmental risk. Heart rate variability (HRV) is widely used to assess autonomic function in these populations, yet findings remain inconsistent. While autonomic differences during the NICU period are well established, less is known about HRV after hospital discharge across childhood and adulthood.
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The role of the oxytocinergic system in oral microbiome composition in children with autism: evidence from a randomized controlled trial of intranasal oxytocin

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By Margaux Evenepoel, Nicky Daniels, Matthijs Moerkerke, Jellina Prinsen, Jean Steyaert, Bart Boets, Marie Joossens, Kaat Alaerts
| Nature Verified
Abstract Atypical oxytocinergic functioning and altered microbiome compositions have both been implicated in autism, with growing evidence of interactions between these systems. However, how exogenous oxytocin influences the oral microbiome remains largely unexplored. This exploratory study examined for the first time how oral microbiome alterations link to oxytocinergic signalling in school-aged autistic (n = 80) and non-autistic children (n = 40).
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