Skip To Main Content
Bart Cortjens on Muck Rack

Bart Cortjens

As seen in: European Journal of Hospital Pharmacy, Thorax
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with Bart

Contact Bart, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

Use of dornase alfa in the paediatric intensive care unit: current literature and a national cross-sectional survey

|
By Bibiche den Hollander, Bart Cortjens, Reinout A Bem, Amsterdam UMC
| European Journal of Hospital Pharmacy Verified
Discussion The main finding from our systematic review of the literature is that the evidence for effectiveness of dornase alfa treatment for airway mucus obstruction in critically-ill children with non-CF diseases in the PICU is scarce, comprising only one RCT in addition to several observational/case studies.
Open in Who Shared Issue with article?

Use of dornase alfa in the paediatric intensive care unit: current literature and a national cross-sectional survey

|
By Bibiche den Hollander, Bart Cortjens, Reinout A Bem, Amsterdam UMC
| European Journal of Hospital Pharmacy Verified
Use of dornase alfa in the paediatric intensive care unit: current literature and a national cross-sectional survey Bibiche den Hollander1, Rosalie S N Linssen1, Bart Cortjens1, Fardi S van Etten-Jamaludin2, Job B M van Woensel1, http://orcid.org/0000-0002-9454-5321Reinout A Bem1 On behalf of the Dutch Collaborative PICU Research Network 1Pediatric Intensive Care Unit, Emma Children's Hospital, Amsterdam UMC, location AMC, Amsterdam, The Netherlands 2Research Support, Medical Library,...
Open in Who Shared Issue with article?

Local dornase alfa treatment reduces NETs-induced airway obstruction during severe RSV infection

|
By Bart Cortjens, Rineke de Jong, Judith G Bonsing, Reinout A Bem
| Thorax Verified
Respiratory syncytial virus (RSV) infection is characterised by airway obstruction with mucus plugs, containing DNA networks in the form of neutrophil extracellular traps (NETs). We investigated the effect of dornase alfa on histopathological NETs-induced airway obstruction and viral load in an age-relevant calf model of severe bovine RSV disease. As compared with the control animals, dornase alfa treatment resulted in a strong reduction of NETs-induced airway obstruction.
Open in Who Shared Issue with article?
See all 5 articles