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Bart Everts on Muck Rack

Bart Everts

The Hague
As seen in: Color Research & Application, Nature, Wiley Online Library, Frontiers, BioRxiv, Cell Metabolism, Cell Press, Library Journal, Hidden City Philadelphia
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Articles

Cell cycle arrest enhances CD8+ T cell effector function by potentiating glucose metabolism and IL-2 signaling - Nature Immunology

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By Nils Mülling, Suzanne van Duikeren, Jacques Neefjes, Hailiang Mei, Bart Everts, Hanna S. Hepp, J. Shirin Mostert, Ward Vleeshouwers
| Nature Verified
Abstract Cell cycle-inhibiting chemotherapeutics are widely used in cancer treatment. Although the primary aim is to block tumor cell proliferation, their clinical efficacy also involves specific effector CD8+ T cells that undergo synchronized proliferation and differentiation. How CD8+ T cells are programmed when these processes are uncoupled, as occurs during cell cycle inhibition, is unclear.
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Integration of mass cytometry and mass spectrometry imaging for spatially resolved single-cell metabolic profiling - Nature Methods

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By Joana B. Nunes, Marieke E Ijsselsteijn, Rick Ursem, Martin Giera, Bart Everts, Ahmed Mahfouz
| Nature Verified
Abstract The integration of spatial omics technologies can provide important insights into the biology of tissues. Here we combined mass spectrometry imaging-based metabolomics and imaging mass cytometry-based immunophenotyping on a single tissue section to reveal metabolic heterogeneity at single-cell resolution within tissues and its association with specific cell populations such as cancer cells or immune cells.
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Immunological factors linked to geographical variation in vaccine responses - Nature Reviews Immunology

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By Gyaviira Nkurunungi, Bart Everts, Alison Elliott
| Nature Verified
Abstract Vaccination is one of medicine’s greatest achievements; however, its full potential is hampered by considerable variation in efficacy across populations and geographical regions. For example, attenuated malaria vaccines in high-income countries confer almost 100% protection, whereas in low-income regions these same vaccines achieve only 20–50% protection.
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