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Articles

Exploring Tafamidis Effects Through PBPK-QSP Modelling

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By Sebastian Polak, Seweryn Ulaszek, Bartek Lisowski, Barbara Wiśniowska
| preprints.org
Submitted: 05 February 2026 You are already at the latest version Background/Objectives: Tafamidis, a transthyretin kinetic stabilizer, increases circulating transthyretin levels in treated patients. While this effect is well documented, its underlying mechanism remains incompletely understood.
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