Behzad Baradaran
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Photodynamic therapy enhances dacarbazine sensitivity of melanoma cells by induction of apoptosis and downregulation of PI3K/AKT signaling pathway
Abstract Dacarbazine (DTIC) is a crucial drug for treating melanoma, but resistance to it poses a significant challenge to effective chemotherapy. Photodynamic therapy (PDT), a minimally invasive, repeatable, and highly selective anti-cancer treatment, has shown promise in recent studies as a potent modulator of chemotherapy sensitivity in different cancerous cells. This investigation aims to explore the effect of photodynamic treatment on the DTIC sensitivity of melanoma cells.
Pulmonary surfactant protein D reduces lung cancer progression associated with decreased IL-4/STAT6 signaling - npj Precision Oncology
Abstract Pulmonary surfactant protein D (SP-D) is an innate immune molecule implicated in lung cancer, where its expression correlates with improved survival and reduced tumor growth. Despite its relevance to lung pathobiology, the transcriptional programs regulated by SP-D and their role in cancer progression and metastasis remain poorly understood.
A comprehensive overview on the crosstalk between microRNAs and viral pathogenesis and infection
1 INTRODUCTION The human genome project ascertained that only about 2% of the human genome encodes proteins, whereas around 98% of the genome does not have any information for protein coding.
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